The lava pools create a choke point that can be altered by the position of the mine cart. There is only a small gap to leave the area you start in (unless you are Selene, then you can jump out over the lava) - take this into consideration when planning your strategy.
The map name 'Red Rob's Border' is a palindrome, which is a sequence of characters which reads the same backward or forward.
There are some good nooks to hide in at each end of the railway tracks.
If you are stuck in a corner you can shoot your way out through the boxes at the top/bottom of the screen.